MEDSCI 203 : Mechanisms of Disease
Medical and Health Sciences
2021 Semester One (15 POINTS)
Capabilities Developed in this Course
|Capability 1:||Disciplinary Knowledge and Practice|
|Capability 2:||Critical Thinking|
|Capability 3:||Solution Seeking|
|Capability 4:||Communication and Engagement|
|Capability 5:||Independence and Integrity|
|Capability 6:||Social and Environmental Responsibilities|
- Understand the origins (aetiologies) and developmental mechanisms (pathogenesis) of diseases, including chronic inflammation (fatty liver disease), abnormalities of immunity (allergies, autoimmunity), bacterial infections, obesity and the loss of insulin efficacy, cardiovascular disease, and tumours. (Capability 1)
- Develop the ability to hold competing theories in mind, and to evaluate their relative merits in accounting for disease development, as exemplified by ongoing controversies over the origins of arterial disease (atheroma and atherosclerosis), and (in cancer) multiple ways by which tumours gain a blood supply and colonise sites remote from the primary tumour. (Capability 2)
- Apply integrative thinking to develop models and hypotheses as to how complex, multifactorial disease conditions may evolve, and how they may be diagnosed (as with genomic and transcriptomic analyses of genetic disease) and treated (as with therapies developed to target proteins specifically altered in cancers ). (Capability 3)
- Develop connections between genetics, relevant environmental conditions, and emerging disease phenotypes, recognising that gene-environment interactions are involved in inflammatory, metabolic and cardiovascular abnormalities (Capability 4)
- Evaluate scientific literature to identify key points and link them together critically in mechanistically illuminating and credible flow diagrams or mind maps. This will be achieved in part by assignments requiring analysis of articles on fatty liver disease, inflammation, heart disease and cancer. (Capability 5)
- Demonstrate the ability to engage in self directed learning when novel concepts require further explanation or elucidation (although staff are available to help with students' difficulties, it is anticipated that students will use resources available to resolve issues arising). (Capability 5)
- Apply knowledge learned in this course to living wisely: theory should relate to lifestyle applications in terms of diet, exercise, stress, cultural and other inputs that ultimately impact on health (such as mediating effects of chronic inflammation, metabolic disease and cardiovascular function). (Capability 6)
|Assignments - online||16%||Individual Coursework|
|Mid-semester Test||20%||Individual Test|
|Final Exam||50%||Individual Examination|
|Laboratories - reports||14%||Individual Coursework|
|Assessment Type||Learning Outcome Addressed|
|Assignments - online|
|Laboratories - reports|
To pass the course as a whole you will need to achieve at least 50% in both the coursework component (coursework = Assignments plus Mid-semester Test) AND at least 50% in the Final Exam.
The Assignments will consist of three online modules designed for students to critically assess published scientific review articles and three practical pathology laboratory-based reports.
This course is a standard 15 point course and students are expected to spend 10 hours per week involved in each 15 point course that they are enrolled in.
For this course, you can expect 32 hours of lectures with tutorials arranged as required, 72 hours of reading, thinking about the content and test/exam preparation, and 45 hours of laboratory work and assignments. The mid-term test is held during a scheduled lecture time.
Attendance is expected at scheduled practical labs to complete coursework components of the course.
At the end of every semester students will be invited to give feedback on the course and teaching through a tool called SET or Qualtrics. The lecturers and course co-ordinators will consider all feedback and respond with summaries and actions.
Your feedback helps teachers to improve the course and its delivery for future students.
Class Representatives in each class can take feedback to the department and faculty staff-student consultative committees.
Course materials are made available in a learning and collaboration tool called Canvas which also includes reading lists and lecture recordings (where available).
Please remember that the recording of any class on a personal device requires the permission of the instructor.
The University of Auckland will not tolerate cheating, or assisting others to cheat, and views cheating in coursework as a serious academic offence. The work that a student submits for grading must be the student's own work, reflecting their learning. Where work from other sources is used, it must be properly acknowledged and referenced. This requirement also applies to sources on the internet. A student's assessed work may be reviewed against online source material using computerised detection mechanisms.
All students are asked to discuss any impairment related requirements privately, face to face and/or in written form with the course coordinator, lecturer or tutor.
Student Disability Services also provides support for students with a wide range of impairments, both visible and invisible, to succeed and excel at the University. For more information and contact details, please visit the Student Disability Services’ website http://disability.auckland.ac.nz
If your ability to complete assessed coursework is affected by illness or other personal circumstances outside of your control, contact a member of teaching staff as soon as possible before the assessment is due.
If your personal circumstances significantly affect your performance, or preparation, for an exam or eligible written test, refer to the University’s aegrotat or compassionate consideration page https://www.auckland.ac.nz/en/students/academic-information/exams-and-final-results/during-exams/aegrotat-and-compassionate-consideration.html.
This should be done as soon as possible and no later than seven days after the affected test or exam date.
In the event of an unexpected disruption we undertake to maintain the continuity and standard of teaching and learning in all your courses throughout the year. If there are unexpected disruptions the University has contingency plans to ensure that access to your course continues and your assessment is fair, and not compromised. Some adjustments may need to be made in emergencies. You will be kept fully informed by your course co-ordinator, and if disruption occurs you should refer to the University Website for information about how to proceed.
Student Charter and Responsibilities
The Student Charter assumes and acknowledges that students are active participants in the learning process and that they have responsibilities to the institution and the international community of scholars. The University expects that students will act at all times in a way that demonstrates respect for the rights of other students and staff so that the learning environment is both safe and productive. For further information visit Student Charter https://www.auckland.ac.nz/en/students/forms-policies-and-guidelines/student-policies-and-guidelines/student-charter.html.
Elements of this outline may be subject to change. The latest information about the course will be available for enrolled students in Canvas.
In this course you may be asked to submit your coursework assessments digitally. The University reserves the right to conduct scheduled tests and examinations for this course online or through the use of computers or other electronic devices. Where tests or examinations are conducted online remote invigilation arrangements may be used. The final decision on the completion mode for a test or examination, and remote invigilation arrangements where applicable, will be advised to students at least 10 days prior to the scheduled date of the assessment, or in the case of an examination when the examination timetable is published.