MEDSCI 314 : Immunology
Medical and Health Sciences
2020 Semester Two (1205) (15 POINTS)
Course Prescription
Course Overview
- Covers some historic landmark discoveries that helped establish immunology as an independent field of research before describing the evolutionary origins of innate and adaptive immunity.
- Describes the architecture of the integrated biological systems that make up the immune system, from its cellular components to its organs.
- Covers the innate arm of the immune system, from complement and phagocytosis to pattern recognition and the acute inflammatory response.
- Concerns the cellular and molecular events underlying the adaptive immune response, from humoral immunity and the diversity of antigen receptors to antigen processing, T cell activation and peripheral tolerance mechanisms.
- Describes the role of the immune system in health and disease, including immunity to bacterial and viral infections, vaccines, immunodeficiency, allergies and hypersensitivity, autoimmunity and tumour immunology.
- Introduces some contemporary topics in immunology including the emerging connection between the historically distinct fields of metabolism and immunology, a memory function for innate immune cells and the influence of the gut microbiome on the immune system.
Capabilities Developed in this Course
| Capability 1: | Disciplinary Knowledge and Practice |
| Capability 2: | Critical Thinking |
| Capability 3: | Solution Seeking |
| Capability 4: | Communication and Engagement |
| Capability 5: | Independence and Integrity |
| Capability 6: | Social and Environmental Responsibilities |
Learning Outcomes
- Understand important historic landmark discoveries that helped establish immunology as an independent field of research and describe the evolutionary origins of innate and adaptive immunity. (Capability 1, 2 and 3)
- Describe the architecture of the integrated biological systems that make up the immune system, from its cellular components to its organs. (Capability 1, 2 and 3)
- Have an understanding of the innate arm of the immune system, from complement and phagocytosis to pattern recognition and the acute inflammatory response. (Capability 1, 2 and 3)
- Have knowledge of the cellular and molecular events underlying the adaptive immune response, from humoral immunity and the diversity of antigen receptors to antigen processing, T cell activation and peripheral tolerance mechanisms. (Capability 1, 2 and 3)
- Describe the role of the immune system in health and disease, including immunity to bacterial and viral infections, vaccines, immunodeficiency, allergies and hypersensivity, autoimmunity and tumour immunology. (Capability 1, 2 and 3)
- Have a basic understanding of some more contemporary topics in immunology. (Capability 1, 2 and 3)
- Perform important experimental techniques to isolate and quantify specific subsets of immune cells and biochemical assays to measure immune responses. (Capability 4 and 6)
- Develop your intellectual and cognitive skills to complete 'on-task' activities. (Capability 2 and 4)
- Evaluate your own progress towards achieving personal and professional goals. (Capability 5)
- Communicate your knowledge and understanding as a future healthcare and/or scientific professional with fellow students, the academic faculty and the community. (Capability 4)
Assessments
| Assessment Type | Percentage | Classification |
|---|---|---|
| Laboratories | 20% | Group & Individual Coursework |
| Essay | 10% | Individual Coursework |
| Test | 15% | Individual Test |
| Final Exam | 55% | Individual Examination |
| 4 types | 100% |
| Assessment Type | Learning Outcome Addressed | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| Laboratories | ||||||||||
| Essay | ||||||||||
| Test | ||||||||||
| Final Exam | ||||||||||
Learning Resources
- Murphy et al. Janeway's Immunobiology, 9th Edition, Garland Science, 2017.
- Delves et al. Roitt's Essential Immunology, 13th Edition, Wiley-Blackwell, 2017.
- Abbas et al. Cellular and Molecular Immunology, 9th Edition, Elsevier, 2017.
- Tak et al. Primer to the Immune Response, 2nd Edition, AP Cell Press, 2014.
Course Contacts
Email: hj.lee@auckland.ac.nz
Phone: 923 1988
Room: 501-002
Workload Expectations
This course is a standard 15 point course and students are expected to spend 10 hours per week involved in each 15 point course that they are enrolled in (inclusive of revision and examination time).
For this course, you can expect 33 hours of lectures (including 3 one-hour laboratory introduction lectures), 2 one-hour tutorials, 3 three-hour laboratory sessions and 3 one-hour laboratory tutorials, 16 hours of work on assignments, 35 hours of reading and thinking about the content and 48 hours of work on test and exam preparation.
Digital Resources
Course materials are made available in a learning and collaboration tool called Canvas which also includes reading lists and lecture recordings (where available).
Please remember that the recording of any class on a personal device requires the permission of the instructor.
Academic Integrity
The University of Auckland will not tolerate cheating, or assisting others to cheat, and views cheating in coursework as a serious academic offence. The work that a student submits for grading must be the student's own work, reflecting their learning. Where work from other sources is used, it must be properly acknowledged and referenced. This requirement also applies to sources on the internet. A student's assessed work may be reviewed against online source material using computerised detection mechanisms.
Inclusive Learning
All students are asked to discuss any impairment related requirements privately, face to face and/or in written form with the course coordinator, lecturer or tutor.
Student Disability Services also provides support for students with a wide range of impairments, both visible and invisible, to succeed and excel at the University. For more information and contact details, please visit the Student Disability Services’ website at http://disability.auckland.ac.nz
Special Circumstances
If your ability to complete assessed coursework is affected by illness or other personal circumstances outside of your control, contact a member of teaching staff as soon as possible before the assessment is due.
If your personal circumstances significantly affect your performance, or preparation, for an exam or eligible written test, refer to the University’s aegrotat or compassionate consideration page: https://www.auckland.ac.nz/en/students/academic-information/exams-and-final-results/during-exams/aegrotat-and-compassionate-consideration.html.
This should be done as soon as possible and no later than seven days after the affected test or exam date.
Student Feedback
At the end of every semester students will be invited to give feedback on the course and teaching through a tool called SET or Qualtrics. The lecturers and course co-ordinators will consider all feedback and respond with summaries and actions.
Your feedback helps teachers to improve the course and its delivery for future students.
Class Representatives in each class can take feedback to the department and faculty staff-student consultative committees.
Student Charter and Responsibilities
The Student Charter assumes and acknowledges that students are active participants in the learning process and that they have responsibilities to the institution and the international community of scholars. The University expects that students will act at all times in a way that demonstrates respect for the rights of other students and staff so that the learning environment is both safe and productive. For further information visit Student Charter (https://www.auckland.ac.nz/en/students/forms-policies-and-guidelines/student-policies-and-guidelines/student-charter.html).
Disclaimer
Elements of this outline may be subject to change. The latest information about the course will be available for enrolled students in Canvas.
In this course you may be asked to submit your coursework assessments digitally. The University reserves the right to conduct scheduled tests and examinations for this course online or through the use of computers or other electronic devices. Where tests or examinations are conducted online remote invigilation arrangements may be used. The final decision on the completion mode for a test or examination, and remote invigilation arrangements where applicable, will be advised to students at least 10 days prior to the scheduled date of the assessment, or in the case of an examination when the examination timetable is published.