MEDSCI 318 : Pharmacokinetics and Drug Toxicity
Medical and Health Sciences
2021 Semester One (1213) (15 POINTS)
Capabilities Developed in this Course
|Capability 1:||Disciplinary Knowledge and Practice|
|Capability 2:||Critical Thinking|
|Capability 3:||Solution Seeking|
|Capability 4:||Communication and Engagement|
|Capability 5:||Independence and Integrity|
|Capability 6:||Social and Environmental Responsibilities|
- Summarise and communicate the role of input, distribution and elimination processes on drug concentration, and explain how physicochemical properties of drugs relate to pharmacokinetic principles. (Capability 1)
- Discuss the patient and environmental factors that influence pharmacokinetics, including the problems encountered with the use of drugs in selected diseases and populations. (Capability 1 and 2)
- Summarise and communicate the role of exposure, concentration and time on toxicity and its consequent impact on biochemistry and the clinical effectiveness of drugs. (Capability 1 and 2)
- Critically discuss the relevance of non-clinical species to the prediction of human drug safety. (Capability 1 and 2)
- Apply scientific reasoning and methods to experimental design for drug concentration and drug toxicity. (Capability 1, 2, 3 and 5)
- Demonstrate competency of a selected range of skills, including observation and measurement, an appreciation of variability, precision and inaccuracy, data analysis and interpretation. (Capability 1, 2, 3, 4 and 5)
- Develop and demonstrate safe and effective animal handling skills and discuss the ethical use of animals in pharmacology in the New Zealand context. (Capability 1, 5 and 6)
|Final Exam||50%||Individual Examination|
|Assessment Type||Learning Outcome Addressed|
This course is a standard 15 point course and students are expected to spend 10 hours per week involved in each 15 point course that they are enrolled in and a total of around 150 hours, which includes revision and examination time.
For this course, you can expect a total of 24 hours of lectures, 24 hours of laboratories, 12 hours of tutorials, 4 hours of tests/exams, and 86 hours of reading and thinking about the content and working on assignments and/or test preparation.
Attendance is required at scheduled activities including labs & tutorials to receive credit for components of the course.
Lectures will be available as recordings. Other learning activities including tutorials & labs will not be available as recordings.
The course will not include live online events.
Attendance on campus is required for the exam.
The activities for the course are scheduled as a standard weekly timetable.
At the end of every semester students will be invited to give feedback on the course and teaching through a tool called SET or Qualtrics. The lecturers and course co-ordinators will consider all feedback and respond with summaries and actions.
Your feedback helps teachers to improve the course and its delivery for future students.
Class Representatives in each class can take feedback to the department and faculty staff-student consultative committees.
Course materials are made available in a learning and collaboration tool called Canvas which also includes reading lists and lecture recordings (where available).
Please remember that the recording of any class on a personal device requires the permission of the instructor.
The University of Auckland will not tolerate cheating, or assisting others to cheat, and views cheating in coursework as a serious academic offence. The work that a student submits for grading must be the student's own work, reflecting their learning. Where work from other sources is used, it must be properly acknowledged and referenced. This requirement also applies to sources on the internet. A student's assessed work may be reviewed against online source material using computerised detection mechanisms.
All students are asked to discuss any impairment related requirements privately, face to face and/or in written form with the course coordinator, lecturer or tutor.
Student Disability Services also provides support for students with a wide range of impairments, both visible and invisible, to succeed and excel at the University. For more information and contact details, please visit the Student Disability Services’ website http://disability.auckland.ac.nz
If your ability to complete assessed coursework is affected by illness or other personal circumstances outside of your control, contact a member of teaching staff as soon as possible before the assessment is due.
If your personal circumstances significantly affect your performance, or preparation, for an exam or eligible written test, refer to the University’s aegrotat or compassionate consideration page https://www.auckland.ac.nz/en/students/academic-information/exams-and-final-results/during-exams/aegrotat-and-compassionate-consideration.html.
This should be done as soon as possible and no later than seven days after the affected test or exam date.
In the event of an unexpected disruption we undertake to maintain the continuity and standard of teaching and learning in all your courses throughout the year. If there are unexpected disruptions the University has contingency plans to ensure that access to your course continues and your assessment is fair, and not compromised. Some adjustments may need to be made in emergencies. You will be kept fully informed by your course co-ordinator, and if disruption occurs you should refer to the University Website for information about how to proceed.
Student Charter and Responsibilities
The Student Charter assumes and acknowledges that students are active participants in the learning process and that they have responsibilities to the institution and the international community of scholars. The University expects that students will act at all times in a way that demonstrates respect for the rights of other students and staff so that the learning environment is both safe and productive. For further information visit Student Charter https://www.auckland.ac.nz/en/students/forms-policies-and-guidelines/student-policies-and-guidelines/student-charter.html.
Elements of this outline may be subject to change. The latest information about the course will be available for enrolled students in Canvas.
In this course you may be asked to submit your coursework assessments digitally. The University reserves the right to conduct scheduled tests and examinations for this course online or through the use of computers or other electronic devices. Where tests or examinations are conducted online remote invigilation arrangements may be used. The final decision on the completion mode for a test or examination, and remote invigilation arrangements where applicable, will be advised to students at least 10 days prior to the scheduled date of the assessment, or in the case of an examination when the examination timetable is published.