MEDSCI 318 : Pharmacokinetics and Drug Toxicity
Medical and Health Sciences
2022 Semester One (1223) (15 POINTS)
Capabilities Developed in this Course
|Capability 1:||Disciplinary Knowledge and Practice|
|Capability 2:||Critical Thinking|
|Capability 3:||Solution Seeking|
|Capability 4:||Communication and Engagement|
|Capability 5:||Independence and Integrity|
|Capability 6:||Social and Environmental Responsibilities|
- Summarise and communicate the role of input, distribution and elimination processes on drug concentration, and explain how physicochemical properties of drugs relate to pharmacokinetic principles (Capability 1)
- Discuss the patient and environmental factors that influence pharmacokinetics, including the problems encountered with the use of drugs in selected diseases and populations (Capability 1 and 2)
- Summarise and communicate the role of exposure, concentration and time on toxicity and its consequent impact on biochemistry and the clinical effectiveness of drugs (Capability 1 and 2)
- Critically discuss the relevance of non-clinical species to the prediction of human drug safety (Capability 1 and 2)
- Apply scientific reasoning and methods to experimental design for drug concentration and drug toxicity (Capability 1, 2, 3 and 5)
- Demonstrate competency of a selected range of skills, including observation and measurement, an appreciation of variability, precision and accuracy, data analysis and interpretation (Capability 1, 2, 3, 4 and 5)
- Discuss the ethical use of animals in pharmacology in the New Zealand context (Capability 1, 5 and 6)
|Mid-semester and end-of-semester assessments||20%||Individual Coursework|
|Final integrated assignment||50%||Individual Coursework|
|Assessment Type||Learning Outcome Addressed|
|Mid-semester and end-of-semester assessments|
|Final integrated assignment|
This course is a standard 15 point course and students are expected to spend 10 hours per week involved in each 15 point course that they are enrolled in.
For this course, you can expect a total of 24 hours of lectures, 24 hours of laboratories, 12 hours of workshops and 90 hours of reading and thinking actively about the content and working on/preparing for assessments.
Attendance is required at scheduled laboratories to receive credit for components of the course.
Lectures will be available as recordings. Other learning activities including workshops will not be available as recordings.
The course will not include live online events.
The activities for the course are scheduled as a standard weekly timetable.
Course materials are made available in a learning and collaboration tool called Canvas which also includes reading lists and lecture recordings (where available).
Please remember that the recording of any class on a personal device requires the permission of the instructor.
At the end of every semester students will be invited to give feedback on the course and teaching through a tool called SET or Qualtrics. The lecturers and course co-ordinators will consider all feedback and respond with summaries and actions.
Your feedback helps teachers to improve the course and its delivery for future students.
Class Representatives in each class can take feedback to the department and faculty staff-student consultative committees.
2021 was the first year this course was offered. Feedback from students was generally positive. Students appreciated the interactions with supportive staff, the workshops and laboratories, and how these complemented the course content and themes. Suggested improvements related to one lab report (identified as being overly large) and a lack of clarity around report writing. These issues will be addressed in 2022 by revising the lab report scope and instructions.
The University of Auckland will not tolerate cheating, or assisting others to cheat, and views cheating in coursework as a serious academic offence. The work that a student submits for grading must be the student's own work, reflecting their learning. Where work from other sources is used, it must be properly acknowledged and referenced. This requirement also applies to sources on the internet. A student's assessed work may be reviewed against online source material using computerised detection mechanisms.
Class representatives are students tasked with representing student issues to departments, faculties, and the wider university. If you have a complaint about this course, please contact your class rep who will know how to raise it in the right channels. See your departmental noticeboard for contact details for your class reps.
Class reps will be elected at the start of the semester and their contact details shared via Canvas.
All students are asked to discuss any impairment related requirements privately, face to face and/or in written form with the course coordinator, lecturer or tutor.
Student Disability Services also provides support for students with a wide range of impairments, both visible and invisible, to succeed and excel at the University. For more information and contact details, please visit the Student Disability Services’ website http://disability.auckland.ac.nz
If your ability to complete assessed coursework is affected by illness or other personal circumstances outside of your control, contact a member of teaching staff as soon as possible before the assessment is due.
If your personal circumstances significantly affect your performance, or preparation, for an exam or eligible written test, refer to the University’s aegrotat or compassionate consideration page https://www.auckland.ac.nz/en/students/academic-information/exams-and-final-results/during-exams/aegrotat-and-compassionate-consideration.html.
This should be done as soon as possible and no later than seven days after the affected test or exam date.
In the event of an unexpected disruption we undertake to maintain the continuity and standard of teaching and learning in all your courses throughout the year. If there are unexpected disruptions the University has contingency plans to ensure that access to your course continues and your assessment is fair, and not compromised. Some adjustments may need to be made in emergencies. You will be kept fully informed by your course co-ordinator, and if disruption occurs you should refer to the University Website for information about how to proceed.
The delivery mode may change depending on COVID restrictions. Any changes will be communicated through Canvas.
Student Charter and Responsibilities
The Student Charter assumes and acknowledges that students are active participants in the learning process and that they have responsibilities to the institution and the international community of scholars. The University expects that students will act at all times in a way that demonstrates respect for the rights of other students and staff so that the learning environment is both safe and productive. For further information visit Student Charter https://www.auckland.ac.nz/en/students/forms-policies-and-guidelines/student-policies-and-guidelines/student-charter.html.
Elements of this outline may be subject to change. The latest information about the course will be available for enrolled students in Canvas.
In this course students may be asked to submit coursework assessments digitally. The University reserves the right to conduct scheduled tests and examinations for this course online or through the use of computers or other electronic devices. Where tests or examinations are conducted online remote invigilation arrangements may be used. In exceptional circumstances changes to elements of this course may be necessary at short notice. Students enrolled in this course will be informed of any such changes and the reasons for them, as soon as possible, through Canvas.